Nano-TiO2: A novel, efficient and recyclable catalyst for the synthesis of 1, 2, 4, 5-tetrasubstituted imidazoles in solvent-free conditions

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Abstract:

A  convenient  and  efficient  one-pot  four-component  synthesis  of  1,  2,  4,  5-tetrasubstituted  imidazoles  using  nano  TiO2  as  a  recyclable  catalyst  is  reported.  The results  show  that  the  methodology  has  several  advantages  such  as  low  loading  of catalyst,  excellent  yield,  short  reaction  time,  operational  simplicity  and  solvent-free conditions.

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Journal title

volume 2  issue 1

pages  1- 9

publication date 2015-06-22

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